Safety and Immunogenicity of a Sabin Inactivated Poliovirus Vaccine.

Inclusion Criteria: * Healthy volunteer aged 2 months (60\~90 days) old without prior vaccination of poliovirus and any contraindication for vaccination; * Guardians of the participants should be capable of understanding the written consent form, and such form should be signed prior to enrolment; * Complying with the requirement of the study protocol; * Axillary temperature ≤ 37.0 °C; Exclusion Criteria: * Preterm or low birth weight infants; * Congenital malformation, developmental disorders, genetic defects, or severe malnutrition; * History of polio; * Severe nervous system disease (epilepsy, seizures or convulsions) or mental illness; * History of allergy to any vaccine, or any ingredient of the vaccine, or serious adverse reaction(s) to vaccination, such as urticaria, dyspnea, angioneurotic edema, abdominal pain, etc; * Autoimmune disease or immunodeficiency/immunosuppressive; * Bleeding disorder diagnosed by a doctor (e.g., coagulation factor deficiency, coagulation disorder, or platelet disorder) , or significant bruising or coagulopathy; * Serious chronic diseases, respiratory diseases, cardiovascular diseases, liver or kidney diseases or skin diseases; * Mother of the participant has HIV infection; * Acute illness or acute exacerbation of chronic disease within the past 7 days; * Had a high fever within the past 3 days (axillary temperature ≥ 38.0°C); * Receipt of any subunit or inactivated vaccine within the past 7 day; * Receipt of any live attenuated vaccine wi…