Role of On-site CT-derived FFR in the Management of Suspect CAD Patients

Inclusion Criteria: * New-onset chest pain suspicious for CAD * Coronary CTA result showed that the diameter stenosis is between 30 and 90% in at least one major coronary artery (coronary artery diameter ≥ 2.5 mm) * Intermediate-to-high pretest probability of CAD based on CAD Consortium Score * No prior evaluation for this episode of symptoms * Agree to participate in this clinical study and sign written informed consent Exclusion Criteria: * Diagnosed or suspected acute coronary syndrome requiring hospitalization or emergent testing * Hemodynamically or clinically unstable condition systolic blood pressure \< 90 mmHg or serious atrial or ventricular arrhythmias * Known CAD with prior myocardial infarction, percutaneous coronary intervention (PCI), coronary artery bypass graft (CABG), or any angiographic evidence of ≥ 50% stenosis in any major coronary artery * Patients with left main branch stenosis ≥ 50% or major coronary artery stenosis \> 90% * Known severe congenital, valvular (moderate and above), or cardiomyopathy process (hypertrophic cardiomyopathy or reduced systolic left ventricular function ≤ 40%) which could explain cardiac symptoms * Unable to provide written informed consent or participate in long-term follow-up.