Comprehensive Computed Tomography Guidance of Coronary Bypass Graft Surgery (NCT03894423) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Comprehensive Computed Tomography Guidance of Coronary Bypass Graft Surgery
United States200 participantsStarted 2019-05-01
Plain-language summary
Apply CT angiography, CT perfusion imaging and advanced image processing techniques to improve revascularization decision-making and surgical strategies in patients undergoing coronary artery bypass graft surgery.
Who can participate
Age range40 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Planned elective CABG for coronary artery disease.
* CABG is the primary indication for surgery (but may include treatment of mild-moderate valvular disease).
* Age: ≥40 years.
Exclusion Criteria:
* Technical feasibility of the cardiac CT exams: redo-CABG, significant arrhythmia/mal-conduction, congenital conditions, severe valvular disease or cardiomyopathy (to the extent that the CT acquisition is technically challenged), inadequate understanding of the English language (to provide consent or follow instructions during the exams).
* Overall safety: unstable clinical condition (clinical heart failure, unstable angina, myocardial infarction \<1 month prior).
* Radiation risk: pregnancy (cannot be ruled out), body weight \>100kg.
* CT contrast medium-related: known allergy, renal failure
* Vasodilator related: known allergy, bronchial asthma requiring daily use of bronchodilators, Mobitz II or 3rd degree AV block, sick sinus node disease, clinically significant carotid artery narrowing, severe aortic stenosis or LVOT narrowing, systolic blood pressure below 90mmHg, (continued) use of dipyridamole or aminophylline.
* Inability to provide informed consent.
What they're measuring
1
Change in myocardial blood flow from baseline measured by cardiac CT