LEC Proliferation in Vivo and In-vitro (NCT03857685) | Clinical Trial Compass
UnknownNot Applicable
LEC Proliferation in Vivo and In-vitro
Austria40 participantsStarted 2019-01-01
Plain-language summary
Investigate the proliferative capacity of individual lens epithelium capsule specimens in vitro and correlate it to the risk of developing PCO
Who can participate
Age range21 Years – 105 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age-related cataract.
* Patients in the age group of 21 years and older.
* Patients with uncomplicated cataract.
* Patients without any relevant systemic or ocular morbidity.
* Patients with well dilating pupils.
* Written informed consent prior to any study specific action.
Exclusion Criteria:
* Patients with complicated cataract.
* Patients with big differences in LOCS scale between the two eyes.
* Patients having corneal pathology.
* Patients with any form of ocular inflammation.
* Patients with glaucoma, retinal pathologies.
* Patients with traumatic cataracts, subluxated and dislocated lens, prior h/o ocular surgery, pseudoexfoliation.
* Any intraoperative complications like posterior capsule rupture.
* In case of pregnancy (pregnancy test will be taken preoperatively in women of reproductive age).
What they're measuring
1
Amount of proliferation of lens epithelial cells (LECs) in-vitro compared to in vivo in the same patient