UnknownNot Applicable

LEC Proliferation in Vivo and In-vitro

Austria40 participantsStarted 2019-01-01

Plain-language summary

Investigate the proliferative capacity of individual lens epithelium capsule specimens in vitro and correlate it to the risk of developing PCO

Who can participate

Age range

21 Years – 105 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age-related cataract. * Patients in the age group of 21 years and older. * Patients with uncomplicated cataract. * Patients without any relevant systemic or ocular morbidity. * Patients with well dilating pupils. * Written informed consent prior to any study specific action. Exclusion Criteria: * Patients with complicated cataract. * Patients with big differences in LOCS scale between the two eyes. * Patients having corneal pathology. * Patients with any form of ocular inflammation. * Patients with glaucoma, retinal pathologies. * Patients with traumatic cataracts, subluxated and dislocated lens, prior h/o ocular surgery, pseudoexfoliation. * Any intraoperative complications like posterior capsule rupture. * In case of pregnancy (pregnancy test will be taken preoperatively in women of reproductive age).

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Amount of proliferation of lens epithelial cells (LECs) in-vitro compared to in vivo in the same patient

Timeframe: 24 months

Trial details

NCT IDNCT03857685

SponsorPrim. Prof. Dr. Oliver Findl, MBA

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2020-05-01

Contact for this trial

Andreea Fisus, MD

01 91021-57564 office@viros.at

View on ClinicalTrials.gov More Posterior Capsule Opacification trials

Who can participate

Age range

21 Years – 105 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.