SuspendedNot Applicable

A Real-Time Magnetic Device Prototype for Temporary Management of Paralytic Lagophthalmos

Stopped: Although six patients completed the test using device prototype before Dec 2019, but due to the large size and shape, we failed to well miniaturize and manufacture a resilient system that stands the test of time for the future trial.

Taiwan12 participantsStarted 2026-08-01

Plain-language summary

To develop a real-time wearable device based on the principle of magnetic force for temporary management of lagophthalmos, and evaluate its efficacy and safety, including synchronous blinks and eye closure, blurred vision, foreign body sensation over cornea or eyeball, burning or hot sensation over facial skin, and erythema or pruritus over eyelid, by performing a human trial on patients with lagophthalmos.

Who can participate

Age range

18 Years – 85 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patient with unilateral lagophthalmos; they are capable of understanding and complying with protocol requirements * Aged 18 years old or older Exclusion Criteria: * Upper eyelid scar, contracture, fibrosis, and atrophy due to previous surgical intervention(s) * Patients with psychiatric (or mental) disorders; they are unable to cooperate or follow the study procedure * Children younger than 18 years of age

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Changes in palpebral gap from the baseline.

Timeframe: 10 minutes after completion of the testing

Changes in visual acuity (blurred vision) from the baseline.

Timeframe: 10 minutes after completion of the testing

Discomfort of the eyeball and condition of the upper eyelid and facial skin based on a dichotomous Likert scale.

Timeframe: 10 minutes after completion of the testing

Changes in palpebral gap from the baseline.

Timeframe: 10 minutes after completion of the second testing within 12 months

Changes in visual acuity (blurred vision) from the baseline.

Timeframe: 10 minutes after completion of the second testing within 12 months

Discomfort of the eyeball and degree of the upper eyelid and facial skin based on a 3-point Likert scale.

Timeframe: 10 minutes after completion of the second testing within 12 months

Trial details

NCT IDNCT03848260

SponsorE-DA Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-08-01

View on ClinicalTrials.gov More Paralytic Lagophthalmos trials

Plain-language summary

Who can participate

Age range

18 Years – 85 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Changes in palpebral gap from the baseline.

Timeframe: 10 minutes after completion of the testing

Changes in visual acuity (blurred vision) from the baseline.

Timeframe: 10 minutes after completion of the testing

Discomfort of the eyeball and condition of the upper eyelid and facial skin based on a dichotomous Likert scale.

Timeframe: 10 minutes after completion of the testing

Changes in palpebral gap from the baseline.

Timeframe: 10 minutes after completion of the second testing within 12 months

Changes in visual acuity (blurred vision) from the baseline.

Timeframe: 10 minutes after completion of the second testing within 12 months

Discomfort of the eyeball and degree of the upper eyelid and facial skin based on a 3-point Likert scale.

Timeframe: 10 minutes after completion of the second testing within 12 months