CompletedNot Applicable

Impact on PCT+ FilmArray RP2 Plus Use in LRTI Suspicion in Emergency Department

France444 participantsStarted 2019-09-01

Plain-language summary

The real-time reporting of PCT results along with viral PCR data from the FilmArray® Respiratory Panel 2 plus in conjunction with an antimicrobial stewardship plan will aid in the proper withholding or withdrawing of antibiotics (ATB) when the collective data is indicative of a viral Lower Respiratory Tract Infection (LRTI). The addition of the FilmArray® RP2plus diagnostic test indicating the presence of a viral infection in subjects presenting with respiratory symptoms could improve the confidence to care-providing physicians to withhold prescribing antibiotics.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. sweats, chills, body aches and pain, temperature \>38°C) and at least one among:
✓. cough, sputum production, dyspnea, chest pain, altered breath sounds at auscultation.

Exclusion criteria

✕. Subject is a prisoner
✕. Subject is a Pregnant
✕. Subject has no social insurance
✕. Subject is enrolled in end of life care
✕. Subject refuses to participate in study procedures
✕. Subject is already enrolled (each patient will only be tested one time with the FilmArray® RP2plus)
✕. Subject has a contraindication (per the discretion of the attending physician) to a nasopharyngeal swab (for example, nose bone fracture or recent history of maxilla-facial surgery)

What they're measuring

Duration of total antibiotic exposure

Timeframe: First 28 days

Trial details

NCT IDNCT03840603

SponsorBioMérieux

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2019-09-01

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