Study in Cat-Allergic Patients With Asthma to Evaluate the Efficacy of a Single Dose of REGN1908-1909 to Reduce Bronchoconstriction Upon Cat Allergen Challenge

Key Inclusion Criteria: * Documented or patient reported history (for at least 2 years) of symptomatic cat allergen-triggered asthma with rhinitis with or without conjunctivitis * No cat exposure at home for the past year and must continue having no exposure at home during the study; cat exposure outside of the home shall be avoided for at least one week prior to any Cat Allergen Challenge and during the defined follow-up period * Less than 10 pack-years of smoking history Key Exclusion Criteria: * Positive human immunodeficiency virus (HIV) test * Positive hepatitis test (HBsAg and hepatitis C antibody) * History of significant multiple and/or severe allergies (including latex gloves) or has had an anaphylactic reaction or significant intolerability to prescription or nonprescription drugs or food * Participation in a prior REGN1908-1909 clinical trial * History of severe anaphylactic or severe asthmatic reactions to cat exposure * Active lung disease other than asthma * Treatment with an investigational drug within 2 months or within 5 half-lives (if known), whichever is longer, prior to screening * Persistent chronic or recurring acute infection requiring treatment with antibiotics, antivirals, or antifungals, or any untreated respiratory infections within 4 weeks prior to screening * History of life-threatening asthma, defined as an asthma episode that required intubation and/or was associated with hypercapnia, respiratory arrest, and/or hypoxic seizures * Treatment of…