Effect of Platelet Inhibition and / or Lipid Lowering in Non-ACS-patients With Positive Troponin (NCT03820466) | Clinical Trial Compass
TerminatedPhase 3
Effect of Platelet Inhibition and / or Lipid Lowering in Non-ACS-patients With Positive Troponin
Stopped: insufficient recruitment due to the pandemic situation
Germany68 participantsStarted 2020-02-21
Plain-language summary
The study evaluates the effect of platelet inhibition and / or lipid lowering in non-ACS-patients with symptoms suggestive for ACS, and elevated high-sensitivity troponin values
Who can participate
Age range50 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patient with symptoms suggestive for ACS presenting within 48 hours after onset in the ER/ Chest Pain Unit (CPU)
* Patient has at least one elevated high-sensitivity troponin I or T value
* Chest pain is classified as non-ACS, despite elevated hsTn (e.g. because of missing troponin dynamics)
* At least 50 years of age
Exclusion Criteria:
* Indication for antiplatelet therapy (e.g transient ischemic attack, or stable coronary artery diseases -CAD) or anticoagulation therapy (such as atrial fibrillation)
* Indication for anti-lipid therapy
* Any evidence of an acute myocardial necrosis (e.g imaging evidence of new regional wall motion abnormality, or significant ST-segment-T wave (ST-T) changes in ECG)
* Untreated clinically significant CAD requiring revascularization
* Hemoglobin value below 8 mg/d, and/or creatinine kinase ā„3 times ULN, and/or AST or ALT ā„3 times ULN
* Active malignancy of any organ system, treated or untreated. Subjects have to be in remission for at least 36 months to be eligible.
What they're measuring
1
Myocardial infarction and/ or cardiovascular death and/ or revascularization
Timeframe: Until last patient has completed 12 months of follow-up