Mindfulness Based Cognitive Therapy (MBCT) During Pregnancy (NCT03809572) | Clinical Trial Compass
TerminatedNot Applicable
Mindfulness Based Cognitive Therapy (MBCT) During Pregnancy
Stopped: Due to restrictions to in-person research due to COVID-19
United States56 participantsStarted 2019-03-22
Plain-language summary
The study is a pilot randomized control trial of a validated intervention, Mindfulness Based Cognitive Therapy (MBCT) adapted for pregnancy, developed to reduce risk for postpartum depression. This study examines emotion regulation as a potential mechanism of action, at both the behavioral and neurobiological level, that carries forward to the postpartum period. A secondary mechanism of action to be explored is cognitive control. This study will also consider other potential influences on treatment response and psychiatric outcomes, including perinatal stress and depressive symptoms. The study population is pregnant women age 21-45.
Who can participate
Age range21 Years – 45 Years
SexFEMALE
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Inclusion criteria
✓. female who is currently pregnant (8-22 weeks gestational age (GA) at time of screen)
✓. 21-45 years old
✓. single gestation
✓. fluently speak English
✓. be available and physically able to attend scheduled group meetings
✓. have a prior history of at least 1 major depressive episode (as determined through psychiatric interviewing).
Exclusion criteria
✕. Magnetic Resonance Imaging (MRI) contraindication (e.g., metal in their body)
✕. major neurological or medical illness (e.g., diabetes, multiple sclerosis)
✕. history of head trauma (loss of conscious \> 2 minutes)
✕. Intelligence Quotient (IQ) \< 80
✕
What they're measuring
1
Center for Epidemiologic Studies Depression Scale - Revised (CESD-R)
Timeframe: 6 Weeks Postpartum
2
Emotion Regulation Questionnaire (ERQ)
Timeframe: 6 Weeks Postpartum
3
Stroop Task
Timeframe: 6 Weeks Postpartum
4
Brain activation during an emotion regulation task