Adipose Derived SVF for Aero-digestive & Enterocutaneous Fistulae

Inclusion Criteria: * Adults ≥ 18 years old * Adults ≤ 90 years old * Fistula or sinus tract opening size between 2 mm and 15 mm in diameter (as measured by comparing its size with the open mouth of a biopsy forceps) * Inpatient or outpatient setting * Recurrent or de novo fistulas or sinus tracts * A prior diagnosis of ADF OR ECF in which the standard therapy has failed or is not applicable * Fistula or sinus tract location may include: * Tracheopharyngeal * Tracheoesophageal * Bronchoesophageal * Gastric, duodenal, jejunal, ileal, colonic or anastomotic -communicating to the skin (cutaneous) * Esophogealgastric anastomosis * Mediastinal anastomotic leak * Fistula etiology may include: * Secondary to previous malignancy with complete remission * Secondary to radiotherapy as long as complete remission for 5 years has been achieved and documented * Congenital with or without previous treatment * Secondary to surgical interventions or endoscopic therapies such as dilation and esophageal manipulation * Post prolonged tracheal intubation * Secondary to inflammatory bowel disease * Secondary to foreign body ingestion * Secondary to thoracic trauma/crush injuries * Secondary to caustic ingestion * Secondary to pneumonectomy or mechanical ventilation * Esophagomalacia * The ability of subjects to give appropriate consent or have an appropriate representative available to do so * The ability of subjects to return for follow up endoscopic assessment as established. Exclusion Criteri…