Stopped: Recruiting difficulties
The aim is to investigate the efficacy of mirtazapine and ondansetron as treatment for hyperemesis gravidarum(HG). The setup is a double-blind multicenter trial where patients suffering from HG will be randomized to treatment with either mirtazapine, ondansetron or placebo (1:1:1).
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Change in nausea and vomiting from baseline to Day 2 (short term) in the mirtazapine group versus the placebo group.
Timeframe: 2 days
Change in nausea and vomiting from baseline to Day 2 (short term) in the ondansetron group versus the placebo group.
Timeframe: 2 days
Change in nausea and vomiting from baseline to Day 14(+/-1) (long term) in the mirtazapine group versus the placebo group.
Timeframe: 14 days
Change in nausea and vomiting from baseline to Day 14(+/-1) (long term) in the ondansetron group versus the placebo group.
Timeframe: 14 days
Change in nausea and vomiting from baseline to Day 2 (short term) in the mirtazapine group versus the ondansetron group.
Timeframe: 2 days