UnknownNot Applicable

Sudden Cardiac Death Stratification in Myotonic Dystrophy Type 1 Patients

Italy70 participantsStarted 2012-02-01

Plain-language summary

The aim of the study is to evaluate if the electrophysiological study (EPS) guided therapy, including the prophylactic implantation of implantable cardioverter defibrillator (ICD), in inducible patients, is able to improve survival in comparison with conventional therapy (CONV strategy) in Myotonic Dystrophy type 1 patients with conduction disorders.

Who can participate

Age range18 Years – 75 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * MD1 diagnosis genetically confirmed * LVEF \>35% on two-dimensional echocardiography * Permanent pacing indication according to the current guidelines Exclusion Criteria: * Electrolyte imbalance * Thyroid disorders * Prior cardiac surgery * Prior cardiac arrest * Prior spontaneous sustained ventricular arrhythmias

What they're measuring

Sudden Cardiac Death

Timeframe: 24 months

Trial details

NCT IDNCT03784586

SponsorUniversity of Campania Luigi Vanvitelli

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-06-30

Contact for this trial

Vincenzo Russo, MD,PhD

0817064149 v.p.russo@libero.it

View on ClinicalTrials.gov More Myotonic Dystrophy 1 trials