Description of the Evolution of Plasma and Urinary Concentrations of Iohexol in a Cirrhotic Patient Population

Inclusion Criteria: * Patients with advanced liver disease, with potential indication for liver transplantation, with or without ascites : * No ascites: 3 patients. * Grade 1 (mild): ascites only detectable by ultrasound examination. 3 patients. * Grade 2 (moderate) and Grade 3 (wide): clinically significant ascites, causing moderate symmetrical distension of the abdomen, or causing severe abdominal distension. 3 patients. * Patients will be over 18 years, affiliated to a social security scheme and give their informed consent. Exclusion Criteria: * Hypersensitivity to the active substance to the products of iodinated contrasts or to any of the excipients mentioned in Composition section * History of major or cutaneous immediate reaction delayed injection of iodinated contrast medium (Omnipaque) * Patients with thyrotoxicosis * Asthmatic patients * Patient with a history of dysthyroidism * Patients with severe cardiovascular disease * Patients with central nervous system disorders especially vascular * Patients with pheochromocytoma * Patients with myasthenia * Patients with sickle cell disease * Patients with autoimmune disease * Patients treated with metformin * Patients requiring anesthesia on the first day of levies * Patients with an injection of iodine contrast during hospitalization and in both previous weeks. Gadolinium injections are not not contraindicated * Patients under guardianship or curatorship or incapacitated give informed consent