Hemorrhagic and thromboembolic complications are common in Veno-venous ECMO therapy. The aim of this study is to provide a detailed analysis of the activity of different coagulation factors and changes in functional coagulation measurements as in rotational thrombelastometry and multiple electrode aggregometry in the course of ECMO therapy.
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Changes in the activity of coagulation factor II [%] during Veno-venous ECMO therapy
Timeframe: Pre-canulation and 6 hours, 1 day, 3 days, 7 days, 11 days, 15 days and 21 days after canulation
Changes in the activity of coagulation factor V [%] during Veno-venous ECMO
Timeframe: Pre-canulation and 6 hours, 1 day, 3 days, 7 days, 11 days, 15 days and 21 days after canulation
Changes in the activity of coagulation factor VII [%] during Veno-venous ECMO
Timeframe: Pre-canulation and 6 hours, 1 day, 3 days, 7 days, 11 days, 15 days and 21 days after canulation
Changes in the activity of coagulation factor VIII [%] during Veno-venous ECMO
Timeframe: Pre-canulation and 6 hours, 1 day, 3 days, 7 days, 11 days, 15 days and 21 days after canulation
Changes in the activity of coagulation factor IX [%] during Veno-venous ECMO
Timeframe: Pre-canulation and 6 hours, 1 day, 3 days, 7 days, 11 days, 15 days and 21 days after canulation
Changes in the activity of coagulation factor X [%] during Veno-venous ECMO
Timeframe: Pre-canulation and 6 hours, 1 day, 3 days, 7 days, 11 days, 15 days and 21 days after canulation
Changes in the activity of coagulation factor XII [%] during Veno-venous ECMO
Timeframe: Pre-canulation and 6 hours, 1 day, 3 days, 7 days, 11 days, 15 days and 21 days after canulation
Changes in the activity of coagulation factor XIII [%] during Veno-venous ECMO
Timeframe: Pre-canulation and 6 hours, 1 day, 3 days, 7 days, 11 days, 15 days and 21 days after canulation