The Study of Efficacy and Safety of Automated PD in Urgent Start Dialysis (NCT03754361) | Clinical Trial Compass
TerminatedNot Applicable
The Study of Efficacy and Safety of Automated PD in Urgent Start Dialysis
Stopped: Patient recruitment difficulties
China34 participantsStarted 2019-01-01
Plain-language summary
This is a multi-center, controlled clinical trial study. The purpose of this study is to examine the efficacy and safety of automated peritoneal dialysis as compared with intermittent haemodialysis for ESRD patients with indications for urgent start dialysis.
Who can participate
Age range18 Years – 75 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* CKD(chronic kidney disease)-5 stage patient whose eGFR(CKD-EPI(chronic kidney disease-epidemiology collaboration))\<15 ml/min/1.73m2,occured uremic symptoms or volume overload need of renal replacement therapy(RRT) within 14 days .
* Prolonged RRT access is not available.
* No dialysis treatment was given within 1 months.
* The vital signs are stable and tolerable in peritoneal dialysis catheterization or central venous catheterization.
* Able to understand the whole process of the trial, voluntarily participate in and sign informed consent.
Exclusion Criteria:
* Maintenance RRT alraedy.
* Serious metabolic disorders ( hyperkalemia and acidosis) cause significant changes in electrocardiogram or other emergency indications to RRT within 24 hours.
* Hypertensive emergencies(diastolic blood pressure\>130mmHg)
* Severe respiratory, circulatory or hepatic failure requires instrumental support or vasoactive drugs to maintain vital signs.
* High catabolic state eg. severe inflammation or trauma
* Absolute contraindication of peritoneal dialysis such as recent abdominal surgery (\<1month), multiple abdominal surgeries.
* Absolute contraindication for hemodialysis such as hemodynamic instability (systolic blood pressure \<80mmHg).
* Pregnant.
* Expected to survive for less than 1 years.
* Plan for kidney transplantation within 3 months.
What they're measuring
1
infective morbidity
Timeframe: At 14 days after the initiation of dialysis