CompletedPhase 2

Repeat Quadratus Lumborum Block to Reduce Opioid Need in Patients After Pancreatic Surgery

United States136 participantsStarted 2019-02-28

Plain-language summary

This phase II trial studies how an additional anesthetic nerve block, called a quadratus lumborum block, works to reduce the need for opioids in patients after pancreatic surgery. Giving an additional regional anesthetic after surgery may hasten the weaning process, reduce the need for opioid medications upon discharge, and reduce the risk of opioid dependence.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients undergoing elective open pancreatic resection for potentially curative intent (pancreaticoduodenectomy or distal pancreatectomy) who would otherwise be treated with QL block + IV-PCA converted to oral pain meds (non-narcotic bundle + opioid pain pill). Exclusion Criteria: * Patients with current or past substance (drug or alcohol) abuse disorder. * Laparoscopic or minimally invasive surgery.

What they're measuring

Number of Participants Discharged Opioid-Free

Timeframe: 90 days from surgery

Trial details

NCT IDNCT03745794

SponsorM.D. Anderson Cancer Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-07-31

Results submitted2022-11-29

View on ClinicalTrials.gov More Pancreatic Carcinoma trials