CompletedNot Applicable

Examining the Impact of Blood Flow Restricted Aerobic Exercise on PGC-1α mRNA Expression in Young Healthy Males

Canada13 participantsStarted 2018-10-01

Plain-language summary

This crossover study investigates the effects of restricting arterial blood flow during cycling exercise on PGC-1α and its upstream signalling pathways. In a randomized order, participants will exercise once for 30 minutes with restricted blood flow and then will exercise once for 30 minutes with no blood flow restriction.

Who can participate

Age range18 Years – 30 Years

SexMALE

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Inclusion Criteria: * 3 hours of physical activity per week * No previous cycling training * No concurrent involvement in another training program * Body mass index \< 30 kg/m2 Exclusion Criteria: * Presence of cardiovascular disease * Presence of metabolic disease * Taking regular oral medication * Current smoker

What they're measuring

Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) messenger ribonucleic acid (mRNA)

Timeframe: 15 minutes before exercise and 3 hours post-exercise for both exercise sessions

Trial details

NCT IDNCT03717948

SponsorQueen's University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-01-28

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