Interventions to Improve Specialty Medication Adherence
United States438 participantsStarted 2019-05-10
Plain-language summary
Patients deemed nonadherent to their specialty medications will be randomized to receive 8 months of patient-tailored adherence interventions and follow up from a specialty pharmacist as needed or the standard of care. Medication adherence will be measured using proportion of days covered (PDC) at 8-months post-randomization to determine if the intervention improved specialty medication adherence.
Who can participate
SexALL
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Inclusion Criteria:
* The same medication (at the Generic Product Identifier level 12) filled ≥4 times in the 12 months before date of import into the study database
* Prescription generated from one of the following Vanderbilt outpatient specialty clinics: Pediatric Rheumatology, Pediatric Gastroenterology/Inflammatory Bowel Disease, adult Vanderbilt Rheumatology clinics, Dermatology, Hematology, Adult Endocrinology, Neurology, Asthma Sinus \& Allergy, Idiopathic Pulmonary Fibrosis, Pulmonary Arterial Hypertension, Cystic Fibrosis, Multiple Sclerosis, Neurology, or a Lipid clinic
* Proportion of Days Covered (PDC) \< 90% over the previous 4 months and 12 months
Exclusion Criteria:
* Prescription issued by a non-VUMC provider
* Planned treatment discontinuation in the subsequent eight months
* More than one unique specialty medication from the same clinic in the previous four months
* Patients with \> 30 gap days in the previous four months and whose last fill was \> 30 days from importing into the study database.
* Any reason for misidentified nonadherence in the previous four months
* Deceased patients
* Incarcerated patients
What they're measuring
1
Median Proportion of Days Covered (PDC) at 8-months Post-enrollment