Negative Pressure Vs. Compression in Venous Ulcers

Inclusion Criteria: * Aged 18 years or more * Provide written informed consent * Venous ulcer present, greater than 10cm2 in surface area * A C6 grading in the CEAP classification Exclusion Criteria: Pregnant (confirmed by β-HCG analysis). Female patients of childbearing potential are advised to adhere to an appropriate form of contraception, and those unwilling to follow contraceptive advice are excluded from the study * Involvement in another clinical trial in the previous six months * Legal incapacity * Patient is bed-ridden or immobile * Ulcer smaller than 10cm2 in surface area * Ischaemic ulcer/s present * Diabetic ulcer/s present * Malignant ulceration/s present * Ulcer exposing bone or tendon * Osteomyelitis * Pseudomonas infection * Presence of gangrene * Deep venous thrombosis (DVT) present * Connective tissue disease present * Presence of any illness that could limit long-term compliance (e.g. epilepsy)