Oxygen Control and Weaning by O2matic to Patients Admitted With an Exacerbation of COPD

Inclusion Criteria: * COPD verified by Forced Expiratory Volume in 1. second (FEV1) divided by Forced Vital Capacity (FVC) \< 0,70 * Admission due to exacerbation in COPD * COPD exacerbation and pneumonia can be included * Expected duration of admission \> 48 hours * Need for oxygen supplementation (SpO2 \<= 88 % on room air) * Cognitively able to participate in the study * Willing to participate and give informed consent Exclusion Criteria: * Need or anticipated need for mechanical ventilation (intermittent Continuous Positive Airway Pressure (CPAP) is allowed) * Major comorbidities causing hypoxemia (Cancer, heart disease, pulmonary emboli) * Asthma or other respiratory condition requiring higher SpO2 than normal for COPD * Pregnancy * Cognitive barriers for participation