Corneal Biomechanics Study (NCT03658239) | Clinical Trial Compass
WithdrawnNot Applicable
Corneal Biomechanics Study
Stopped: Organizational Issues.
0Started 2018-12
Plain-language summary
The goal of the study is to investigate relationship between the corneal response to a temporary increase in intraocular pressure and corneal mechanical properties.
Who can participate
Age range
18 Years – 55 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria
A person is eligible for inclusion in the study if he/she:
* Is an adult between the ages of 18 and 55.
* Is under 250 pounds.
Exclusion Criteria
A person will be excluded from the study if he/she:
* Is under the age of 18 or over the age of 55 yrs.
* Weighs more than 250 pounds.
* Has clinically significant dry eye.
* Has glaucoma.
* Has hypertension.
* Has prior CVA.
* Has cardiovascular disease.
* Has lower extremity joint injury, damage, or replacement.
* Has baseline bradycardia.
* Has any orthopaedic injuries.
* Is pregnant.
* Has hiatal and ventral hernias.
* Has vertigo.
* Has acid reflux (GERD).
* Is undergoing myopia control treatment (e.g. atropinisation, Ortho-K, bifocal contact lenses etc.).
* Has conditions or has undergone procedures resulting in significant corneal irregularity (e.g. keratoconus, corneal transplant, etc.). This does not include astigmatism and basic refractive errors.
* Has any ocular or systemic diseases that, in the opinion of the PI/SI, would interfere with obtaining a measurement.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.