Micropore Closure Kinetics at Various Body Sites (NCT03657277) | Clinical Trial Compass
CompletedNot Applicable
Micropore Closure Kinetics at Various Body Sites
United States46 participantsStarted 2018-10-01
Plain-language summary
The study to be performed will define the rate of skin barrier recovery following micropatch application to the skin on the upper arm, volar forearm, and abdomen in healthy subjects.
Who can participate
Age range18 Years – 50 Years
SexALL
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Inclusion Criteria:
* 18 - 50 years of age
* Healthy, non-obese men and women
* Identify as African American or Black, Asian, Hispanic or Latino, Caucasian/White, bi-/multiracial or other
Exclusion Criteria:
* Unable to give consent
* Severe general allergies requiring chronic treatment with steroids or antihistamines
* Previous adverse reaction to micropatch application
* Previous history of keloids
* Known allergy or adverse reaction to medical tape/adhesive or aloe vera
* Any inflammatory diseases of the skin; psoriasis, atopic dermatitis, and blistering skin disorders
* Diseases associated with altered immune function (including but not limited to: rheumatoid arthritis, diabetes, lupus, HIV/AIDS)
* Any subjects taking medication that impairs the immune system (including but not limited to corticosteroids, TNF inhibitors, monoclonal antibodies, chemotherapy agents)
* Any current malignancy or history of malignancy present at the micropatch application sites
* Eczema or scaling present at the application sites
* Any current inflammation or irritation present at the application sites (including but not limited to: rash, inflammation, erythema, edema, blisters)
* BMI\>29.9
* Uncontrolled mental illness that would, in the opinion of the physician, affect the subject's ability to understand or reliably participate in the study
* Subjects taking medications in the following therapeutic classes will be excluded: HMGCoA reductase inhibitors ("statins"), oral or topical steroids…