European Alpha-Mannosidosis Participant

Inclusion Criteria: * Informed consent is obtained from the participant's parent/legal guardian * The participant is aged between 2 months and 18 years of age * The participant has a family history of Alpha-Mannosidosis or is at risk for Alpha-Mannosidosis according to one or more of the following symptoms: recurrent infections, skeletal abnormalities, hearing impairment-deafness, progressive neurological symptoms, impairment of mental functions, gingival hypertrophy, dysmorphic facial features, motoric disturbances of no obvious etiology Exclusion Criteria: * Informed consent is not provided by the partici-pant's parent/legal guardian * The participant is younger than 2 months or older than 18 years * The participant has no family history of Alpha-Mannosidosis and is not at risk for Alpha-Mannosidosis (represents none of the following symptoms): recurrent infections, skeletal abnormalities, hearing impairment-deafness, progressive neurological symptoms, impairment of mental functions, gingival hypertrophy, dysmorphic facial features, motoric disturbances of no obvious etiology