The purpose of the protocol, is to describe the use of cabozantinib tablets as monotherapy or in combination with nivolumab including the number of dose reductions, dose interruptions and terminations due to (serious) adverse events in subjects with advanced or metastatic renal cell carcinoma (mRCC) treated in real-life clinical setting in 1st line treatment.
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The proportion of subjects with dose reduction of cabozantinib due to Serious Adverse Events/Adverse Events (SAEs/AEs)
Timeframe: 2 years
The proportion of subjects with dose interruption of cabozantinib and/or nivolumab due to SAEs/AEs
Timeframe: 2 years
The proportion of subjects with termination of cabozantinib /cabozantinib-nivolumab combination due to SAEs/AEs
Timeframe: 2 years
Number of injection delayed of nivolumab due to SAE/AE
Timeframe: 2 years