Innate Immunity in Eosinophilic Esophagitis (NCT03640975) | Clinical Trial Compass
CompletedNot Applicable
Innate Immunity in Eosinophilic Esophagitis
France35 participantsStarted 2018-07-11
Plain-language summary
The main aim of this study is to assess the expression of innate lymphoid cells in the esophageal mucosa of children with eosinophilic esophagitis (EoE) and in control subjects
Who can participate
Age range1 Year – 18 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* children 1-18 years
* presenting with symptoms suggestive of EoE
* requiring an upper gastrointestinal endoscopy with biopsies of the esophageal mucosa in order to confirm or exclude the diagnosis
* Children paired for age in whom an endoscopy performed to explore symptoms of EoE revealed another condition (peptic oesophagitis, achalasia), or children paired for age in whom an endoscopy with biopsies has been performed to explore chronic abdominal or epigastric pain or suspected chronic inflammatory bowel disease, will be include as control subjects
Exclusion Criteria:
* immune deficiency
* auto immune diseases