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AKI Cardiosurgery Diagnostic Study (AKI-CDS)

Germany40 participantsStarted 2018-07-27

Plain-language summary

Acute kidney injury (AKI) is a common and major complication of cardiac surgery. The aim of this study is to evaluate the use of a fragment of proencephalin in plasma and other biomarkers as specific markers for early diagnosis of AKI and the need of renal replacement therapy after cardiac surgery.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Female or male, at least 18 years old * Ability to consent to the study by patient or legal representative * Cardiac surgery with use of extracorporeal circulation (ECC) * Bypass (\> 2; ACB) or bypass + heart valve surgery * Two or three heart-valve operation Exclusion Criteria: * Dialysis-dependent patients with chronic, end-stage renal failure * Pre-existing renal replacement therapy * Infused prognosis (expected death in ≤ 12 hours despite maximal therapy) * Inability to consent of participation in the research project, of the patient or of the patients representative * Aortic surgery * Endocarditis * (Only) partial sternotomy (eg. aortic valve surgery)

What they're measuring

AKI 0 h

Timeframe: after operation (surgery): 0 hours

AKI 6 h

Timeframe: after operation (surgery): 6 hours

Trial details

NCT IDNCT03632538

SponsorUniversity of Rostock

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-07

Contact for this trial

Martin Sauer, MD

+493814946409 martin.sauer@uni-rostock.de

View on ClinicalTrials.gov More Acute Kidney Injury trials