Epstein-Barr Virus Implication in Peri-implantitis: Towards an Innovative Etiopathogenic Model.

Inclusion Criteria: * Adult patient * Patient with at least one dental implant with a fixed implant-supported prostheses * Patient with a peri-implantitis * (Patient with healthy dental implant for control group) * patients having read and understood the information note on the study and signed the informed consent form. * patients affiliated to the social security system. Exclusion Criteria: * Patient with severe hematologic disease * Patients with previous or current acute illness or severe chronic cardiovascular, renal, hepatic, gastrointestinal, allergic, endocrine, neuro-psychiatric, considered by the investigator to be incompatible with the conduct of the study. * Patients treated with retinoids, oral bisphosphonates, oral anticoagulants or anticonvulsants. * Patient have or have had cancer of the upper aerodigestive tract treated by radiotherapy. * Patient taking a steroidal or non-steroidal anti-inflammatory, anti-cancer or immunosuppressive chemotherapy in the last 6 months. * Patient monitoring considered difficult by the investigator. * Patient with oral dermatitis or adverse occlusion. * Patient with autoimmune disease * Patient with a linguistic or mental incapacity to understand information * Patient trust under curators or judicial protection * Patient participating in another clinical study.