Improving Self-Efficacy, Resolving Inflammaging Allo HSCT Survivors in Personal Training (NCT03609203) | Clinical Trial Compass
CompletedNot Applicable
Improving Self-Efficacy, Resolving Inflammaging Allo HSCT Survivors in Personal Training
United States25 participantsStarted 2018-09-10
Plain-language summary
This protocol is a pilot study of a personalized and supervised 10-week strength training program to improve self-efficacy and resolve biomarkers of inflammaging in a cohort of allogeneic hematopoietic transplant (HCT) long-term survivors versus healthy controls.
Who can participate
Age range18 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Healthy Volunteers: must be the friends or relatives of the cancer patients enrolled in this study.
Inclusion Criteria:
* HCT recipients
* Age ≥ 18 years
* Greater than 6 months after completing systemic multiagent chemotherapy (greater than 12 months for HCT participants) at the time of enrollment. Maintenance chemotherapy is allowed
* In remission from cancer Off immunosuppression, or on a stable immunosuppression regimen with prednisone doses ≤ 20 mg daily, with no changes planned to the immunosuppression regimen during the study period
* Karnofsky performance status ≥ 50% (Appendix III)
* Platelet count ≥ 50,000 without transfusions
* Absolute neutrophil count ≥ 1
* Willing to complete weekly strength training sessions for 10 consecutive weeks and complete all pre- and post-testing (self-efficacy survey and research blood draw)
* Currently reside within the Minneapolis-St. Paul metro area
* Has an adult (age ≥ 18) friend or relative who is willing to serve as an exercise partner and healthy control for the study
* If known diabetic: Stable doses of medications to treat diabetes within 4 weeks prior to enrollment
* Willing and able to sign voluntary written consent
* Healthy Controls
* Age ≥ 18 years
* Karnofsky performance status ≥ 50%
* Willing to complete weekly strength training sessions for 10 consecutive weeks and complete all pre- and post-testing (self-efficacy survey and research blood draw)
* Currently reside within the Minneapol…
What they're measuring
1
Self-reported outcomes of self-efficacy
Timeframe: Week 10
Trial details
NCT IDNCT03609203
SponsorMasonic Cancer Center, University of Minnesota