Safety and Efficacy Study of Absnow Absorbable ASD Closure System For Treating ASD Patients

Inclusion Criteria: * Age ≥3 , weight ≥10Kg * Secundum left-to-right shunt ASD with hemodynamic significance * Distance from the defect edge to coronary vein sinus, superior and inferior vena cava, pulmonary vein≥5mm and AV valve should be ≥7mm * The atrial septum length (stretched diameter) should be greater than the diameter of left disk Exclusion Criteria: * Patients of primum, venous sinus and coronary sinus ASD * Patients with atrial septum defect ≥26mm * Patients with other structural heart disease in addition to ASD * Patients with complication of obstructive pulmonary arterial hypertension, Eisenmenger syndrome * Infective endocarditis patients * Patients with hemolysis or hemorrhagic disease, unhealed ulcer or any taboo about aspirin (except being able to take other anti-platelet agent for consecutive six months) within one month before implantation * Patients with thrombosis(especially in left atrium or left atrial appendage thrombus) as shown by echocardiography * Patients with known condition of hypercoagulation status * Patients who have undergone heart surgery in the past * Patients allergic to PLLA * Patients refusing to sign the informed consent form * Patients with poor compliance on disease-related treatment and poor cooperation on follow-up visits * Patients that are in pregnancy or lactation, or planned for pregnancy or get a positive pregnancy test result during the screening period * Patients that have participated in any clinical trial that may affec…