Safety of LAIV4 in Children With Asthma

Inclusion Criteria: * Children between 5-11 years of age, inclusive, at enrollment * Participant must have a current diagnosis of persistent asthma (Physician diagnosis of asthma and current prescribed use of a long-acting controller medication. For purposes of this study, we have considered "controller" medications to be any single or combination use of long-acting medications used to prevent asthma exacerbations and to achieve long-term control of asthma (as compared to short-acting rescue medication).) * Parent(s) or legal guardian(s) must provide written, informed consent and participant must provide assent as appropriate for age prior to initiation of study procedures and according to local IRB requirements * Parent(s) or legal guardian(s) and participant must be willing and able to comply with planned study procedures and be available for all study visits * Is in good health, other than their asthma, as determined by medical history * English or Spanish literate (only English-speaking participants will be included at the Cincinnati and Duke sites) * Intention of being available for entire study period and complete all relevant study procedures, including follow-up using at least one of the following methods: phone calls, text messages, or emails Exclusion Criteria: * Acute illness and/or a reported oral temperature of ≥ 100.4°F within 72 hours prior to enrollment (this may result in a temporary delay of vaccination) * Use of antipyretic medication during the precedin…