Study Comparing Caspofungin to Placebo for the Treatment of ICU Intra-abdominal Candidiasis

Inclusion Criteria: * Age ≥ 18 years old * Covered by national health insurance * Admitted to ICU after surgery for intra-abdominal infection : * With suspected intra-abdominal candidiasis defined by a Peritonitis score ≥ 3(1) * Or with documented intra-abdominal candidiasis defined by positive direct examination or positive culture of peritoneal fluid collected intraoperatively. * With written and signed informed consent Exclusion Criteria: * Allergy to caspofungin * Life expectancy ≤ 48h * Expected withdrawal of treatment * Radiological drainage without surgery * Severe hepatic impairment (Child-Pugh C score) * Pregnant or lactating women * Immunodepression (treatment including long-term corticosteroids, anti-TNF or disease including transplant patients) * Infected acute pancreatitis * Ascites fluid infection