Stopped: Study halted prematurely
This phase I trial investigates the side effects and best dose of CD19 positive (+) specific CAR-T cells in treating patients with CD19+ lymphoid malignancies, such as acute lymphoblastic leukemia, non-Hodgkin lymphoma, small lymphocytic lymphoma, or chronic lymphocytic lymphoma. Sometimes researchers change the genetic material in the cells of a patient's T cells using a process called gene transfer. Researchers then inject the changed T-cells into the patient's body. Receiving the T-cell infusion may help to control the disease.
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Incidence of adverse events
Timeframe: Up to 15 years
Maximum tolerated dose (MTD) as determined by dose limiting toxicity (DLT)
Timeframe: Up to 30 days post-infusion