Stereotactic radiosurgery or hypofractionated radiotherapy of the resection cavity after metastasectomy in cancer patients with brain metastases
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria:
* Patient underwent surgery for single brain metastasis arising from solid neoplasia (lung, breast, melanoma, kidney, colorectal), with initial histological diagnosis, or selected cases with a resected lesion and a further non-resected lesion (from 1 to 2 lesions), treatable with SRS / IGRT of the surgical cavity
* Patient ≥ 18 years
* Willngness to participate in the study, written informed consent
* Performance Status according to WHO 0-I
* Good general conditions and organ function
* Newly diagnosed chemotherapy-naïve disease or controlled systemic disease
* Good bone marrow, renal and hepatic function
* Stable steroid dose or reduced for at least 5 days
Exclusion Criteria:
* History of previous brain irradiation
* Pregnancy or breastfeeding
* Histological diagnosis other than lung, breast, melanoma, kidney and colorectal malignancy