Effect of Preoperative Intravenous Dexamethasone on Postoperative Pain After Primary Total Hip Ar… (NCT03542617) | Clinical Trial Compass
UnknownPhase 4
Effect of Preoperative Intravenous Dexamethasone on Postoperative Pain After Primary Total Hip Arthroplasty
Thailand57 participantsStarted 2016-10-05
Plain-language summary
To compare the effects of preoperative intravenous Dexamethasone between 10 mg and 40 mg with placebo on Postoperative Pain After Primary Total Hip Arthroplasty
Who can participate
Age range18 Years – 80 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age \> 18 years
* Undergoing Elective, Primary, unilateral Total Hip arthroplasty
* American Society of Anesthesiology (ASA) physical class 1-3
* BMI \< 40 kg/m2
Exclusion Criteria:
* History of previous musculoskeletal injury on the same hip
* History of prior surgery on the same unilateral hip
* History of adverse effects from medication utilized in this study
* Contraindication to spinal anesthesia
* History of psychiatric disorders or cognitive impairment
* Contraindication to Corticosteroid
* Poorly controlled Diabetes mellitus
* History of ischemic heart disease or peripheral arterial disease or cerebrovascular disease
* Hepatic insufficiency (Child-Pugh score \> 5)
* Renal insufficiency (Creatinine clearance \< 30 mL/min)
* History of cataract or glaucoma or ocular hypertension
What they're measuring
1
Visual analogue scales for pain during five-metre walking (0-100)