Testing the Efficacy of Mindfulness-based Stress Reduction in the Prevention of Perimenopausal De… (NCT03526523) | Clinical Trial Compass
CompletedNot Applicable
Testing the Efficacy of Mindfulness-based Stress Reduction in the Prevention of Perimenopausal Depression
Canada104 participantsStarted 2018-07-05
Plain-language summary
Depression is the leading cause of disability worldwide and a risk factor for other diseases. While women are at elevated risk for depression in general, the menopause transition is a particularly vulnerable time for many women, with the risk for depression increasing 2-4 fold. The objective of this research study is to determine whether mindfulness-based stress reduction (MBSR), an 8-week structured intervention involving meditation and yoga, has any beneficial mood effects for women undergoing this vulnerable time.
Who can participate
Age range42 Years – 55 Years
SexFEMALE
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Inclusion Criteria:
* in the early or late menopause transition according to the Stages of Reproductive Aging Workshop (STRAW+10) criteria, defined as menstrual cycle length 7+ days shorter or longer than usual or the presence of amenorrhea lasting 60 days or more (but less than 12 months)
Exclusion Criteria:
* current psychiatric diagnosis of major depressive disorder, bipolar disorder, a psychotic disorder or any other psychiatric diagnosis rated "severe" based on DSM-5 criteria
* use of medications affecting mood (e.g. antidepressants) or ovarian hormone levels (e.g. oral contraceptives)
* pregnant or nursing
* currently receiving a psychological treatment for depression
* major life-threatening health conditions.
What they're measuring
1
Depressive symptoms
Timeframe: 6 months (CES-D completed every 2 weeks)