Pre-operative Alcohol Skin Solutions in Fractured Extremities
United States8,485 participantsStarted 2018-08-21
Plain-language summary
The prevention of infection is an important goal influencing peri-operative care of extremity fracture patients. Standard practice in the operative management of extremity fractures includes sterile technique and pre-operative skin preparation with an antiseptic solution. The available solutions kill bacteria and decrease the quantity of native skin flora, thereby decreasing surgical site infection (SSI). While there is extensive guidance on specific procedures for prophylactic antibiotic use and standards for sterile technique, the evidence regarding the choice of antiseptic skin preparation solution is very limited for extremity fracture surgery.
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Patients 18 years of age or older.
✓. Open fracture of the appendicular skeleton.
✓. Received or will receive definitive fracture treatment with a surgical implant(s) (i.e., internal fixation, external fixation, joint prosthesis, etc.).
✓. Open fracture wound management that includes formal surgical debridement within 72 hours of their injury.
✓. Will have all planned fracture care surgeries performed by a participating surgeon or delegate.
✓. Informed consent obtained.
✓. Patient enrolled within 3 weeks of their fracture.
Exclusion criteria
✕. Fracture of the hand (distal to radial carpal joint).
✕. Patients who did not or will not receive the allocated pre-operative surgical preparation solution due to a medical contraindication.
✕
What they're measuring
1
Number of Participants With a Superficial Incisional Surgical Site Infection (SSI)
Timeframe: Within 30 days of the patient's last planned fracture management surgery
2
Number of Participants With a Deep Incisional Infection
Timeframe: Within 90 days of the patient's last planned fracture management surgery