Hemoadsorption With CytoSorb® in Post-Cardiac Arrest Syndrome

Adult (≥18 years old) patients admitted to the ICU after CA, at risk of PACS as defined by the presence of at least one of the following characteristics (at any time within 24hrs of CA): * Need for a vasoconstrictor (norepinephrine dose \> 0.2 µg/kg/min to maintain MAP \> 60-70 mmHg, , or equivalent vasoconstrictor agent) for at least one hour * Serum lactate level \> 6 mmol/l * Time to ROSC \> 25 minutes Exclusion Criteria: * Evidence for patient's refusal to participate in clinical trials * Non commitment for ongoing medical therapy (imminent withdrawal of care) * Cardiac arrest caused by hemorrhagic shock * Contraindications to therapeutic heparinization * Shock of primary cardiac origin (LVEF \<20%) * Platelet count \<20 G/L * Deep immunosuppression state, as defined by neutrophils \<1 G/L or CD4 \<200 /mm3 * Pregnancy * Acute sickle cell crisis * Refractory cardiac arrest with ECMO implantation * Need for renal replacement therapy at time of randomization * Concomitant enrolment in another study * Non availability of the research team at time of eligibility at time of randomization