European Paediatric AFM Associated With EV-D68 Follow-up Study. (NCT03499366) | Clinical Trial Compass
UnknownNot Applicable
European Paediatric AFM Associated With EV-D68 Follow-up Study.
Norway40 participantsStarted 2018-04-09
Plain-language summary
The study is a follow-up study on children with acute flaccid paresis associated with enterovirus D68 infection. Only children living in Europe are eligible. The study aim is to clarify the outcome of the disease and investigate possible clinical correlation with outcome, including initial severity, demographic characteristics, treatment and MRI findings.
Who can participate
Age range1 Day – 18 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Acute flaccid paresis (AFP) at onset, and
* Enterovirus D-68 polymerase chain reaction (PCR) positive in any specimen in a timely sample (+/- 3 weeks from onset of paresis), and
* Age \<18 years at onset, and
* Magnetic resonance imaging (MRI) of spine and brain at onset with signs of myelitis.
Exclusion Criteria:
* Major trauma
* central nervous system (CNS) malignancy
* Bleeding or infarctions in CNS
* Previous demyelinating disease
* Other infections cause of myelitis is more likely
* Patient and/or legal guardian is not able/willing to sign the consent form
What they're measuring
1
Total Hammersmith Functional Motor scale- score at follow-up