The L-PRF block is a combination of bone substitute with L-PRF. The use of a L-PRF block in bone augmentation therapies could enhance and improve bone regeneration.
The primary objective of this study is to evaluate if the use of autologous leukocytes and platelet rich fibrin accelerate and promotes bone regeneration in the sinus in comparison with the standard sinus lift procedure procedure.
Who can participate
Age range18 Years
SexALL
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Inclusion Criteria:
* Males and females ≥ 18 years of age.
* Ability to understand the nature of the proposed surgical procedure and sign an informed consent form.
* ASA I and ASA II.
* In need of an implant in the posterior region of the maxilla,
* RBH of \<4 mm or RBH \>4 mm but no transcrestal approach possible (due to anatomy).
* Healthy oral mucosa and no active periodontal disease.
* Edentulous sites consisting of native, non-augmented bone.
Exclusion Criteria:
* General contraindications for implant placement and/or surgical treatment.
* Acute infection or residual lesions in the edentulous sites.
* Acute maxillary sinus pathosis.
* Ongoing inflammatory and/or autoimmune diseases of the oral cavity.
* Patients with poor oral hygiene who are not amenable to improvement.
* Immunosuppressants, corticosteroids, or bisphosphonate
* History of malignancy, radiotherapy, or chemotherapy for malignancy within the past five years.
* Smoker \> 10 cigarettes.
* Uncontrolled insulin-dependent diabetes.
* Pregnant or lactating women.
* Alcohol and drug abuse.