Misoprostol Prior to IUD Insertion in Nullipara

Inclusion Criteria: * Nulliparous women * No chirurgical procedure in the cervix * Wish to use IUD as a contraceptive method Exclusion criteria are as follows: * Presence of active cervical infection visible upon speculum exam (purulent cervicits) * Pelvic Inflammatory Disease (PID) or other uterine infection diagnosed within the last 3 months (based on self-report or clinical documentation) * Pregnancy ending less than 6 weeks prior to enrollment in study * History of prior IUD placement * History of uterine cavity abnormality including Mullerian tract anomalies and leiomyomas distorting uterine cavity shape * History of uterine surgery * Allergy or intolerance to misoprostol or other prostaglandin * Undiagnosed abnormal vaginal bleeding * Malignancy of the genital tract * Allergy to any component of the IUD or Wilson's disease (for copper- containing IUDs) * Pre-procedure use of anesthesia or analgesia (including use of narcotics, benzodiazepines, or use of anesthetic beyond use at the tenaculum site)