Phlogenzym® in Patients With Acute Thrombophlebitis - Efficacy and Tolerance

Inclusion Criteria: * male ог female patients with thrombophlebitis in the upper extremities (with ог without varicosis); * age \~ 18 years; * acute thrombophlebitis in the lower leg * moderate to severe pain as monitored on a visual analog scale (VAS, value ≥ 3 cm) * pain under pressure * presence of at least three of the following symptoms: skin redness, hyperthermia, phlebitic cords, feeling of heaviness and tenseness. Exclusion Criteria: * known deep phlebothrombosis * flourishing ulcus cruris * arterial occlusive disease * peripheral neuropathy * malignant disease * concomitant concomitant treatment ог а therapy which ended less than 7 days before baseline with corticosteroids, diuretics, anticoagulative agents, platelet aggregation inhibitors and systemic/topical use of anti-inflammatory agents, other preparations for veins and analgesics; * known intolerance against the active ог the inactive ingredients of the study medication (especially lactose); * pregnancy * lactation, * known alcohol or drug abuse * participation in another clinical study