Long-term Endogenous Androgen Priming in Bologna Criteria Poor Responder Patients - A Pilot Study

Inclusion Criteria: * Age 18 - 41 years * BMI \< 30 kg/m2 * Ovarian reserve, according to the ESHRE Bologna Criteria measured within two months prior to stimulation start Bologna criteria: At least two of the following three features present: * Advanced maternal age (≥40 years) or any other risk factor for POR * A previous POR (≤3 oocytes with a conventional stimulation protocol) * An abnormal ovarian reserve test (i.e. antral follicle count \< 5-7 follicles or AMH\< 0.5 - 1.1 ng/mL) * Poor responder if - Two previous episodes of POR after maximal stimulation (300 IU) * Receiving GnRH-antagonist co-treatment during ovarian stimulation * Agreement to participate in the study, and to disclose any medical events to the investigator. The subject must be willing and able to comply with the protocol requirements for the duration of the study. * Have given written informed consent with the understanding that the subject may withdraw consent at any time without prejudice to future medical care. Exclusion Criteria: * Chronical medical conditions like Diabetes, Crohns disease, Thyroid disease, Hepatitis B and Sexually Transmitted Diseases Simultaneous participation in an interventional clinical trial.