Role of Intestinal Protozoa and Helminths in the Course of Ulcerative Colitis

Inclusion Criteria: * Patients with ulcerative colitis before therapy and surgery * Residents of Tashkent region which does not have any complaints from the gastrointestinal tract (control group) Exclusion Criteria: * Patients with a diagnosis of Crohn's disease * Patients with a toxic megacolon, * Patients with a abdominal abscess, - * Patients with a symptomatic colonic stricture, * Patients with a stoma, * Patients with a a history of colectomy, * An increased risk of infectious complications (e.g. as a result of recent pyogenic infection, enteric pathogens detected on stool analysis, active or latent tuberculosis, immunodeficiency, hepatitis B or C, or recent live vaccination), * Clinically meaningful laboratory abnormalities, * Pregnancy or lactation, * An unstable or uncontrolled medical disorder, * An anticipated requirement for major surgery, * Colonic dysplasia or adenomas, * Malignant neoplasms. * Patients which operated, * Ever used immunosuppressants or biological drugs * In the presence of pathologic bacteria in gut microbiota, including Clostridium difficile, Salmonella spp, Shigella spp, Campylobacter spp, Yersinia spp, and Mycobacteria.