Robotic Nipple-Sparing Mastectomy Vs Conventional Open Technique

Inclusion Criteria: * Invasive breast cancer, Ductal Carcinoma In Situ, Breast Related Cancer Antigens mutation carriers. * Any age * Candidates to nipple-sparing mastectomy and immediate breast reconstruction * Negative preoperative assessment of nipple-areola complex * Absence of skin involvement * Low probability to have positivity of nipple-areola complex tissue intra-operative frozen section * Breast volume ≤ Bra IV; from cup A to D * No hard smoking (hard smoking defined as \>20 cigarettes/day) * Low and intermediate risk for anesthesia (ASA Scale) * Written informed consent must be signed and dated by the patient and the investigator prior to inclusion * Patients must be accessible for follow-up Exclusion criteria: * Previous thoracic radiation therapy for any reason * Inflammatory Breast Cancer * Skin involvement * Pre-operative diagnosis (radiological or cytological) of nipple-areola complex disease * Pregnancy * Patients with psychiatric, addictive, or any disorder, which compromises ability to give informed consent for participation in this study * Uncompensated Diabetes Mellitus * Hard smokers (hard smoking defined as \>20 cigarettes/day) * High risk for anesthesia