The purpose of this study is to assess immunogenicity and safety of GSK Biologicals' HZ vaccine when its first dose is co-administered with a pneumococcal polysaccharide conjugate vaccine (Prevenar13) in adults aged ≥50 YOA, as compared to the control group where the two HZ/su doses are administered subsequent to Prevenar13.
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Percentage of Subjects With a Vaccine Response for Anti-glycoprotein E (Anti-gE) in Co-Ad Group
Timeframe: One month post-dose 2 (Month 3)
Anti-gE Antibody Concentrations
Timeframe: One month post-dose 2 (at Month 3 for the Co-Ad and Month 5 for the Control group).
Anti-pneumococcal Antibody Titers
Timeframe: At one month post-dose 1 (Month 1)
Adjusted Geometric Mean Concentrations (GMCs) for Anti-gE Antibody
Timeframe: One month post-dose 2 (at Month 3 for the Co-Ad and Month 5 for the Control group).
Adjusted Geometric Mean Titers (GMTs) of Anti-pneumococcal Antibodies
Timeframe: At one month post-dose 1 (Month 1)