Safety and Feasibility of ADRCs Treatment To Patients With Thermal Wounds

Inclusion Criteria: * Males or females age ≥ 18 to ≤ 65 * BMI \> 20 kg/m2 * Burn TBSA 20% - 50% * At least one deep partial thickness and/or full thickness thermal burn ≥ 250 cm2 on the arms, legs, back, abdomen or chest that is anticipated to be covered with autologous meshed STSG meshed and that has not been treated previously with a biologic dressing such as Alloderm® or Integra® * Ability to safely undergo tissue harvest that is anticipated to yield \>150mL of adipose tissue at a site that is free from infection * Donor site availability for skin graft harvest * Able to provide written informed consent signed by either the patient or their legally authorized representative * Women and men of child-bearing potential agreeing to use contraception during the study. Acceptable methods include surgical sterility, IUDs, hormonal contraception or double barrier methods Exclusion Criteria: * Subjects with burns \> 3rd degree (i.e. involvement of deeper tissues, such as muscle, tendons, or bone) * Subjects with electrical or chemical burns * Subjects with significant inhalation injuries necessitating intubation and mechanical ventilation or requiring \> 50% FI02 on a continuous basis to maintain oxygenation (02 sat \> 90%) * In the opinion of treating physician, patient not expected to survive beyond 30 days * Pre-existing condition requiring current use of immunosuppressive medication or systemic steroids * Pregnant or lactating status. Pregnancy as determined by a positive pr…