Ketamine Versus Lidocaine Nebulization for Awake Fiberoptic Intubation (NCT03414879) | Clinical Trial Compass
CompletedPhase 4
Ketamine Versus Lidocaine Nebulization for Awake Fiberoptic Intubation
Egypt60 participantsStarted 2018-01-15
Plain-language summary
This randomized double-blinded study is performed to compare ketamine versus lidocaine for nebulization for awake nasal fiberoptic intubation as regard efficacy and side effects.
Who can participate
Age range21 Years – 50 Years
SexALL
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Inclusion Criteria:
* American Society of Anesthesiologists (ASA) physical status I and II of both sexes with body weight from 60-90 kg, and planned for elective awake nasal fiberoptic intubation due to expected difficulty in airway management (e.g. limited mouth opening, trismus, mandibular/ maxillary swellings or tumors, ludwig's angina, or other indications).
Exclusion Criteria:
* body weight \< 60 kg or \> 90 kg
* uncooperative, with mental or psychological problems
* known allergy to any of the study drugs
* pregnancy
* hypertension
* cardiac disease
* liver or renal impairment
* epilepsy,
* asthmatic,
* previous bad experience of awake intubation,
* emergency operations or
* coagulation abnormalities