Lumbar Plexus Block Versus Quadratus Lumborum Block for Primary Anterior Total Hip Arthroplasty (NCT03409900) | Clinical Trial Compass
CompletedNot Applicable
Lumbar Plexus Block Versus Quadratus Lumborum Block for Primary Anterior Total Hip Arthroplasty
United States44 participantsStarted 2019-03-04
Plain-language summary
Total hip arthroplasty (THA) is one of the most successful orthopedic procedures to effectively relieve pain and restore function in patients with end stage osteoarthritis. In an attempt to accelerate recovery many orthopedic surgeons have opted to utilize a direct anterior approach (DAA) as opposed to the more traditional posterolateral approach (PLA). The literature supports that DAA is superior to PLA with regard to lower blood loss, less pain, shorter hospital stay, and faster rehabilitation. Traditionally the study team has performed Lumbar Plexus blocks (LPB) to provide post-operative analgesia for total hip arthroplasty. The quadratus lumborum block (QLB) is a newer regional analgesic technique that may be as effective as LPB at providing pain control following DAA hip arthroplasty. This study is designed to compare the efficacy, with regards to post-operative pain management, between LPB and QLB following a DAA total hip arthroplasty.
Who can participate
Age range
18 Years – 95 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Any patient between the ages of 18 and 95 years undergoing a primary elective, unilateral DAA total hip arthroplasty.
Exclusion Criteria:
* If the patient uses more than 40mg of Oxycodone equivalents per 24 hours or is on extended release opioid formulations.
* Indication for surgery is secondary to trauma and/or hip fracture
* If there is a contraindication to the performance of a regional block
* Concomitant anticoagulation use or documented coagulopathy
* Infectious or dermatologic conditions in the area of block placement that would otherwise increase the risk of peripheral nerve blockade
* Presence of progressive neurologic deficit effecting peripheral nerves
* Allergy or adverse reaction to study drugs to include: fentanyl, epinephrine, and amide local anesthetics
* American Society of Anesthesia Physical Classification score \> or = to 4
* Allergies to study drugs other than local anesthetic
* BMI \> 40
* Patient refusal
* Pregnancy
* Institutionalized individuals
* Extremes of age: Age \> 95 or \< 18
* Non English speaking or inability to reliably participate in the study
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Verbal numeric pain score with hip flexion at 6hrs (Numeric Rating Scale (NRS))