Assay for the Pancreatic Polypeptide: an Help for Clinical Practice Guidelines in Classification … (NCT03396146) | Clinical Trial Compass
CompletedNot Applicable
Assay for the Pancreatic Polypeptide: an Help for Clinical Practice Guidelines in Classification of the Diabetes
France36 participantsStarted 2018-06-14
Plain-language summary
The purpose of this study is to evaluate global endocrine function within type 1 and type 3c diabetic patients, helping pancreatic polypeptide measurement.
Who can participate
Age range18 Years
SexALL
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Inclusion Criteria:
* Patients aged 18 years or older
* Patients with type 1 diabetes with anti-GAD and / or IA2 and / or Znt8 positive antibodies, or characteristic clinical history, with and without exocrine deficiency (\*)
* Patients with chronic alcoholic pancreatitis or cystic fibrosis origin (type 3c diabetes), complicated with diabetes defined by HbA1c\> 6.5% or treated with oral anti-diabetic and / or insulin
* Patients who have given informed and written consent to participate in research
* Patients affiliated to a social security scheme (\*): The exocrine deficiency is defined by an assay of fecal elastase:
* without deficit of exocrine function = fecal elastase = /\> 100 μg / g
* with deficit of exocrine function = fecal elastase \<100 μg / g
Exclusion Criteria:
* Pregnancy
* Severe renal impairment (eDFG \<45 mL / min / 1.73 m²)
What they're measuring
1
Measurement of pancreatic polypeptide for calculating the area under the curve