Intrapleural Docetaxel Administration Using Medical Pleuroscopy in Malignant Effusion With Lung Cancer

Inclusion Criteria: * Age ≥ 20, and NSCLC patients with malignant pleural effusion and related symptoms * ECOG ≤ 2 * Blood test ANC≥ 1500/mm3, Hb ≥ 8.0g/dl, platelet count ≥ 100000/mm3 Serum creatinine ≤ 1.8mg/dl, Total bilirubin within normal limits, Transaminases ≤ 1.5 x UNL, Alkaline phosphatase ≤ 2.5 X UNL BUN ≤ 25mg/dl, Creatinine clearance ≥ 50ml/min * Negative serum or urine pregnancy test for women for childbearing age * Patients who provide written informed consent for the study Exclusion Criteria: * Age \< 20 * Patients who were previously perfomed pleurodesis * Patients who were previously treated with thoracic radiosurgery * Patinet with bilateral pleural effusion * Age ≥ 80yrs * Patients with histories of hypersensitivity to Docetaxel * Patients with cardiovascular, respiratory, hepatic, renal, gastrointestinal, neunological disease, asthma, MI, stroke, arrhythmia, uncontrolled hypertionsion, etc. that would effect absorption, distribution, and metabolism of IP or be risk factors during IP administrion. * Patients who could not understand the study procedure